NKF KDOQI GUIDELINES

Clinical Practice Guidelines and Clinical Practice Recommendations
2006 Updates
Hemodialysis Adequacy
Peritoneal Dialysis Adequacy
Vascular Access


I.  CLINICAL PRACTICE GUIDELINES FOR PERITONEAL DIALYSIS ADEQUACY

WORK GROUP BIOGRAPHIES

Joanne Bargman, MD, FRCPC, received her MD cum laude at the University of Toronto in 1978. After medical residency in Toronto, she was chosen as an exchange resident in Melbourne, Australia, where she completed her postgraduate year 3. She undertook nephrology training at Stanford University and, as a fellow of the Medical Research Council of Canada, spent almost 3 years in physiology research examining mechanisms of urinary concentration. She assumed a staff nephrologist position at the Toronto Western Hospital in 1985 and worked in the PD unit with Dimitrios Oreopoulos. She has published more than 120 articles and delivered more than 200 lectures internationally on subjects ranging from PD to glomerulonephritis and systemic lupus erythematosus. She is Director of the PD Program and also Co-Director of the Renal-Rheumatology Lupus Clinic at the University Health Network in Toronto. Dr Bargman is a council member of the International Society of Nephrology and the International Society of PD. She is the recipient of major teaching awards at the undergraduate and postgraduate levels at the University of Toronto. Dr Bargman has received research funds, grants, or contracts from Amgen, Baxter Healthcare, Fresenius Medical Care, and Gambro Healthcare.

Peter G. Blake, MD, FRCPC, MBBCh, is a Professor of Medicine and Chair of the Division of Nephrology at the University of Western Ontario and London Health Sciences Centre. He is a member of the Canadian Society of Nephrology Work Group on PD, was the editor of 2 major textbooks in nephrology, and is Editor-in-Chief of Peritoneal Dialysis International. His areas of interest include dialysis with particular regard to the development of PD, adequacy and nutrition in PD, trends in patient outcomes, and the economics of dialysis. Dr Blake has received lecture fees from Amgen, Baxter Healthcare, and Ortho Biotech.

John M. Burkart, MD (Co-Chair), is Professor of Medicine/Nephrology at Wake Forest Baptist Medical Center in Winston-Salem, NC. He is Corporate Medical Director of the Wake Forest University Outpatient Dialysis Centers. He attended medical school at Rush Medical College in Chicago, IL, and did his residency training and fellowship at the Bowman Gray School of Medicine of Wake Forest University. He has served on the PD Adequacy Work Group since its formation, currently as the Co-Chair. He is treasurer of the International Society for PD. He is a member of the Centers for Medicare and Medicaid Services advisory council for reimbursement based on case-mix. He has authored many chapters on PD in major nephrology text books and parts of Up to Date and is interested in all clinical aspects of PD and hemodialysis. Dr Burkart has received research funds, grants, or contracts from Baxter Healthcare, Genzyme, and Fresenius Medical Care.

Fredric O. Finkelstein, MD, is Chief of Nephrology, Hospital of St Raphael, and Clinical Professor of Medicine at Yale University, New Haven, CT. Dr Finkelstein has been involved in continuous ambulatory PD since 1979, when he started a freestanding continuous ambulatory PD facility in New Haven, CT. He has written extensively on a variety of issues involving PD therapy. He currently is a member of the Council of the International Society of PD and is on the Editorial Board of Peritoneal Dialysis International. Dr Finkelstein has received research funds, grants, or contracts from Baxter Healthcare and Renal Research Institute.

Thomas A. Golper, MD, FACP, trained at Indiana University and the Oregon Health Sciences University and currently is Professor of Medicine (Nephrology) at Vanderbilt University Medical Center in Nashville, TN. He has held positions on the Board of Directors of the Renal Physicians Association and American Association of Kidney Patients, served as the PD Adequacy Work Group Chair for the first 2 versions of KDOQI, and remains on the Work Group and Steering Committee. He led the Network 9 Peritonitis and Catheter Survival Study and has served on the International Society of PD Ad Hoc Committee for Peritonitis for many iterations of its guidelines. His interests remain in the field of dialysis and the administrative aspects of nephrology practice. Dr Golper has received research funds, grants, or contracts from Amgen, Baxter Healthcare, Genzyme, Ortho Biotech, and Roche.

Angellina Graham, RN, graduated in 1995 with an associate degree in nursing. She is currently employed by Wake Forest Outpatient Dialysis at Piedmont Dialysis Center, serving in the role of Charge Nurse in the Hometraining Department and has also assisted with numerous clinical trials.

Beth Piraino, MD (Co-Chair), received her BS from the University of Pittsburgh. She attended medical school at the Medical College of Pennsylvania and graduated magna cum laude. She did her subsequent training in Internal Medicine and Nephrology at the University of Pittsburgh Health Center, after which she joined the faculty of the University of Pittsburgh School of Medicine, rising through the ranks over the years to her current position as tenured Professor of Medicine and Associate Dean of Admissions. Dr Piraino's major research interest has been to improve outcomes of patients on PD therapy, in particular, by decreasing infectious complications. She has published widely in the area of PD, with numerous presentations at national and international meetings. She was Secretary for the International Society of PD from 2001 to 2006. She is Director of the PD Program at the University of Pittsburgh and Co-Medical Director of Dialysis Clinic Inc of Oakland. She received the prestigious Life Time Achievement Award at the 24th Annual Dialysis Conference in February 2004 for contributions to the care of PD patients. Dr Piraino has received research funds, grants, or contracts from Paul Teschan Fund through Dialysis Clinic Inc. and Baxter Healthcare.

Susan Stark, MS, RD, CSR, LDN, is a dietitian specialist at the University of Pittsburgh Medical Center, Presbyterian Hospital. She is a member of the American Dietetic Association.

Bradley A. Warady, MD, is Chief of Nephrology and Director of Dialysis and Transplantation at The Children's Mercy Hospital and Professor of Pediatrics at the University of Missouri-Kansas City School of Medicine. Dr Warady's clinical and research focus is end-stage renal disease, with particular emphasis on PD. He established the Pediatric PD Study Consortium and is a member of the Board of Directors of the North American Pediatric Renal Transplant Cooperative Study. He currently serves as Co-Principal Investigator of the International Pediatric Peritonitis Registry and the National Institutes of Health–funded Chronic Kidney Disease in Children (CKiD) study. He co-edited the books CAPD/CCPD in Children and Pediatric Dialysis and has published more than 200 articles and book chapters. He is a council member of the International Society of PD and has been a member of the KDOQI PD Adequacy, Pediatric Nutrition, and Pediatric Bone Work Groups for the National Kidney Foundation. Dr Warady also serves as an Associate Editor for Peritoneal Dialysis International and sits on the Editorial Board of Pediatric Nephrology. Dr Warady has received research funds, grants, or contracts from Amgen and Watson Pharmaceuticals.

CONSULTANTS TO THE KDOQI PEDIATRIC PERITONEAL DIALYSIS GUIDELINE AND CPRs

Steven R. Alexander, MD, FACP, is Chief of Division of Nephrology at Department of Pediatrics at Stanford University School of Medicine. Dr Alexander is the Founder and Director of the Annual Symposium on Pediatric Dialysis and he is serving on the Editorial Board for Pediatric Transplantation and International Journal of Artificial Organs. Dr Alexander has received research funds, grants, or contracts from Amgen, AstraZeneca Inc., Genentech Inc., National Institutes of Health, Southwest Pediatric Nephrology Study Group (SPNSG), and Watson Pharmaceuticals.

Michel Fischbach, MD, is Chief of the Pediatric Department at the University Hospital of Strasbourg and Professor of Pediatrics at the University Louis Pasteur of Strasbourg, France. Dr Fischbach's clinical and research focus is end stage renal disease with a special interest in hemodialysis and peritoneal dialysis. As a member of the European Pediatric Dialysis Work Group (EPDWG), he published as a first author on the European Peritoneal Dialysis Guidelines (2002) for children. He is also the primary author in more than 100 international articles on dialysis in children and he serves as an Associate Editor for Pediatric Nephrology, Dialysis section.

Denis F. Geary, MB, MRCP(UK), FRCP(C), is a Professor at Department of Pediatrics in University of Toronto and Chief at Division of Nephrology, The Hospital for Sick Children. He is the past-President of the Canadian Association of Pediatric Nephrologists and his current areas of interest include nocturnal hemodialysis for children, antenatally diagnosed renal disease, growth in children with renal failure, and anemia in children with chronic renal failure. Dr Geary has received research funds, grants, or contracts from Amgen and Hoffman La Roche.

Franz Schaefer, MD, is Professor of Pediatrics and Chief of the Pediatric Nephrology division at Heidelberg University Medical Center. He established the Mid European Pediatric Peritoneal Dialysis Study Group (MEPPS) and the European Study Group on Progressive Chronic Kidney Disease in Children (ESCAPE). He currently serves as Co-Principal Investigator of the International Pediatric Peritonitis Registry and he is also a member of the European Pediatric PD Working Group. He has co-edited the book “Pediatric Dialysis” and has published more than 220 articles and book chapters. In addition, he is a current council member of the European Society for Pediatric Nephrology and serves as pediatric liaison officer at the council of the International Society of Peritoneal Dialysis. Dr Schaefer also serves as an Assistant Editor for Pediatric Nephrology and sits in the Editorial Boards of Peritoneal Dialysis International, Current Pediatric Reviews and Biomed Central Nephrology. Dr Schaefer has received research funds, grants, or contracts from AstraZeneca, Baxter Healthcare, Fresenius Medical Care, IBM, Pfizer, and Roche.

Cornelis H. Schröder, MD, PhD, is Director of the Pediatric Nephrology, Dialysis, and Transplantation Department at the Wilhelmina Children's Hospital and Professor of Pediatric Nephrology at the University of Utrecht, The Netherlands. His main research focuses are hereditary glomerular diseases and kidney replacement therapy, with particular emphasis on peritoneal dialysis. He is a member of the European Pediatric Dialysis Working Group, and has published several guidelines on behalf of this group. He is the author of more than 150 articles and book chapters in the field of pediatric nephrology.

Professor Alan R. Watson, FRCP, is Director of the Children & Young People's Kidney Unit, Nottingham City Hospital and Professor of Paediatric Nephrology at the University of Nottingham, UK. His research interests have been in clinical nephrology including nutrition, dialysis, psychosocial aspects and ethics. He is the group coordinator of the European Dialysis Working Group, which has produced 7 published guidelines to date. Prof. Watson has published over 200 articles and book chapters and he is a Council member of the European Society for Paediatric Nephrology since 2003. He is also currently on the Editorial Boards of the British Journal of Renal Medicine and Peritoneal Dialysis International.