NKF KDOQI GUIDELINES

KDOQI Clinical Practice Guidelines for Bone Metabolism and Disease in Chronic Kidney Disease


BIOGRAPHICAL SKETCHES OF WORK GROUP MEMBERS

Kline Bolton, MD, FACP, is Professor of Medicine at the University of Virginia in Charlottesville, where he is Chief of the Division of Nephrology and Director of the Nephrology Clinical Research Center, Kidney Center and Renal Operations. He has received special honors from organizations ranging from the American Society for Clinical Investigation to the International Society of Nephrology. He has published many articles in journals ranging from the American Journal of Kidney Diseases and Kidney International to Immunologic Renal Diseases, and contributed to numerous text books, including the Textbook of the Autoimmune Diseases and the Textbook of Nephrology. He is Chairman of the Renal Physicians Association Work Group on Appropriate Preparation of Patients for Renal Replacement Therapy. His research interests are in refining the epitope(s) involved in causing Goodpasture’s syndrome, treating glomerulonephritis, and disease management of CKD and ESRD.

Jack W. Coburn, MD, FACP, (Work Group Vice-Chair), is Professor of Medicine at the UCLA School of Medicine. In addition to serving as a staff physician at the West Los Angeles VA Medical Center, where he had previously been the Chief of the Nephrology Section, Dr. Coburn is an attending physician at Cedars-Sinai Medical Center, Los Angeles, Brotman Medical Center, Culver City, and Century City Hospital, Los Angeles, and a visiting physician at UCLA Medical Center. A recipient of the Alumni Achievement Award from the University of Redlands and the Lifetime Achievement Award for Research in Vitamin D from the 9th Annual Vitamin D Workshop, he has served past and present as a long-time member on several editorial boards including the American Journal of Nephrology, Kidney International, and the American Journal of Kidney Diseases, and has over 450 published scientific papers, reviews, and editorials to his credit. Dr. Coburn is on the Medical Advisory Boards of Bone Care International, R & D Laboratories and Amgen, Inc., and has also consulted with Genzyme Corporation.

Glenn M. Chertow, MD, MPH, is Assistant Professor of Medicine in Residence at the University of California, San Francisco (UCSF) and Director of Clinical Services in the Divisions of Nephrology at Moffitt-Long Hospitals and UCSF-Mt. Zion Medical Center. He serves as Medical Director of the Dialysis programs at both sites. Dr. Chertow’s research interests are focused on epidemiology, health services research, and clinical trials in acute and chronic kidney disease. He has written numerous papers on end-stage renal disease, acute renal failure, mineral metabolism, nutrition, and costs and outcomes of dialysis therapy. He is currently Associate Editor of the Journal of Renal Nutrition, and on the Editorial Board of Journal of the American Society of Nephrology. He serves on the Board of Directors of the TransPacific Renal Network (Network #17) and has been active in numerous volunteer positions with the National Kidney Foundation, American Kidney Fund, and American Society of Nephrology. He was Vice Chair of the Work Group that developed the KDOQI Clinical Practice Guidelines for Nutrition of Chronic Renal Failure. Dr. Chertow has received research support from, and has served as an advisor to, Amgen, Inc., Genzyme, Inc., and GelTex Pharmaceuticals, Inc.

Keith A. Hruska, MD, is the Ira M. Lang Professor of Medicine at Barnes-Jewish Hospital at Washington University School of Medicine and a Professor of Medicine at Washington University School of Medicine, where he also completed a fellowship in the Renal Division. He was previously the Director of the Renal Division at the Jewish Hospital of St. Louis. Dr. Hruska’s areas of research and special interest include renal osteodystrophy, mineral homeostasis and bone cell signal transduction, and he has received special honors from the American Association of Physicians. He has served as the principal investigator in several long-term studies and has been published well over 200 times. Dr. Hruska is on the Medical Advisory Board of Bone Care International and has received funding or compensation from it as well as AlloSource, Creative BioMolecules, Inc., and Monsanto/Pharmacia.

Craig B. Langman, MD, is a Tenured Professor of Pediatrics at Northwestern University Medical School and Head of Nephrology and Mineral Metabolism and Director of Dialysis at Children’s Memorial Medical Center in Chicago. Dr. Langman’s research has focused on the anatomical, biochemical, and clinical expression of inherited or acquired disorders of calcium, phosphorus, and vitamin D metabolism in infants, children, and adolescents, and he has pioneered the use of noninvasive testing to assess bone cell function in children. Dr. Langman has had more than 125 articles in his discipline published and serves on the Editorial Advisory Boards of Advances in Renal Replacement Therapy and Pediatric Endocrinology. He previously served on the Editorial Advisory Board of Pediatric Nephrology. Dr. Langman has been President of the American Board of Pediatrics sub-board of Pediatric Nephrology, the American Society of Pediatric Nephrology, and the Council of American Kidney Societies. He has served on the work group for the KDOQI Clinical Practice Guidelines for Nutrition of Chronic Renal Failure as well as on the Scientific Advisory Board and the Public Policy and Executive Committees of the Council of Pediatric Urology and Nephrology Committees of the NKF and on the Growth Advisory Board of the North American Pediatric Renal Transplant Cooperative Study. Dr. Langman is on the Academic Advisory Board of Total Renal Care, Inc, and has been a consultant for many pharmaceutical laboratories, health-care companies, and health-care-related foundations, including Merck USA, Roche Pharmaceuticals, Abbott Laboratories, and the Oxalosis and Hyperoxaluria Foundation.

Hartmut Malluche, MD, is Professor of Medicine and Chief of the Division of Nephrology, Bone and Mineral Metabolism at the University of Kentucky Medical Center, Lexington, KY., where he is also the Robert G. "Robin" Luke Chair in Nephrology. Dr. Malluche is on the Active Scientific Staff at the Shriner’s Hospital for Crippled Children, Lexington Unit, Lexington, KY. He has been a Scientific Reviewer for the National Institutes of Health (NIH) and an advisor to the Food & Drug Administration’s Division of Cardio-Renal Drug Products Meeting. Dr. Malluche is an ex-officio member of the General Clinical Research Committee, and he is the University of Kentucky Institutional Representative for the American Society of Clinical Investigation. He is also a member of the Educational Review Committee for the Department of Preventative Medicine and Environmental Health. Dr. Malluche has been a visiting professor at universities throughout Europe and the United States and is a frequent guest speaker within the academic and health-care communities. He is a member of numerous professional societies, including the American Society of Nephrology, the International Society of Nephrology, the American Physiological Society, and the European Dialysis and Transplant Association (EDTA). He has served as a member of the Editorial Board of the American Journal of Kidney Diseases and Nephron and is the American Editor of Clinical Nephrology, in addition to having been published over 400 times. Dr. Malluche has received several grants from the NIH and other organizations including the Veterans Administration.

Kevin J. Martin, MB, BCh, FACP, is Professor of Medicine and Director of the Division of Nephrology at Saint Louis University School of Medicine, St. Louis, MO. He has also served as the Chief of the Nephrology Section at John Cochran Veterans Administration Hospital, St. Louis, MO. Dr. Martin completed a fellowship and an advanced research fellowship in the renal division of the Washington University School of Medicine, St. Louis, MO, as well as fellowships with the National Kidney Foundation of Eastern Missouri and Metro-East. He is on the Executive Committee of the Department of Internal Medicine at St. Louis University and was Chairman of the NIH General Medicine B Study Section and the Endocrinology Study Section of the Veterans Administration, and has been both a board member and President of the NKF of Eastern Missouri and Metro-East. Dr. Martin is a member of the American Federation for Clinical Research, the American Society of Nephrology, the International Society of Clinical Investigation, American Society of Nephrology and the NKF. He is on the Editorial Board of the American Journal of Physiology and has over 150 publications. Dr. Martin has been a consultant to Amgen, Inc., and Abbott Laboratories, and has also received funding from Genzyme Corporation.

Shaul G. Massry, MD, (Work Group Chair) is Professor Emeritus of Medicine, Physiology and Biophysics, at the Keck School of Medicine, University of Southern California. He has received honorary doctorates from several universities across Europe and is an honorary member of many professional societies worldwide, including the Italian, Polish, Bulgarian, Hungarian, Czechoslovakian, Indian, and Israel Societies of Nephrology. He is also an honorary member of the Belgian, Polish, Russian, and Bulgarian Academies of Science as well as the Royal College of Physicians of Ireland, Thailand, and London. In addition to the NKF’s David Hume Memorial Award and the Distinguished Scientific Achievement Award from the American Heart Association, Greater Los Angeles Affiliate, Dr. Massry has been the recipient of numerous other awards from universities and societies throughout the world, including the first Leo Ambard Gold Medal from the University of Strasbourg. Dr. Massry has served as the Editor-in-Chief of several journals including Nephron, and the American Journal of Nephrology, and is a reviewer for many other journals. He is a past President of the NKF and past Chairman of the NKF’s National Medical Advisory Board, and has served with other organizations such as the NIH, the International Society of Nephrology, the American Heart Association, Greater Los Angeles Affiliate, and the International Society of Nutrition and Metabolism in Renal Disease. Dr. Massry has been a frequent guest speaker at national and international meetings and a visiting professor at many universities across the globe, and he has an extensive list of publications to his credit. Dr. Massry is a consultant to Genzyme Corporation and has participated in Advisory Board Meetings of Abbott Laboratories and Amgen, Inc.

Linda McCann, RD, CSR, LD, is Nutrition Services Manager at Satellite Dialysis Centers, Inc., Redwood City, CA. She is also Chairperson of the Dietitian Advisory Board for Genzyme Corporation and a Nutrition Consultant for Baxter Healthcare Corporation. Ms. McCann is a member of the American Dietetic Association (ADA) and the ADA Renal Practice Group, for which she served as Chairperson of the Standards of Practice Committee and a Test Writer and Reviewer in Renal Specialization. In addition to serving on the Volunteer Development Committee and the Editorial Board of Advances in Renal Replacement Therapy for the NKF, she is also on the NKF Council on Renal Nutrition, where she has been Nominating Committee Chairperson, and on the Editorial Board of the Journal of Renal Nutrition. Ms. McCann is on the Editorial Board of Dialysis and Transplantation, and has been published numerous times in a variety of publications. She is also a frequent guest lecturer in both the health-care and business sectors. Ms. McCann has received the Award of Distinguished Achievement from the CRN of Northern California, was honored as a Recognized Renal Dietitian (RRD) by the NKF Council on Renal Nutrition, and has twice been the recipient of the NKF’s Distinguished Service Award. In addition to Baxter and Genzyme, she has also consulted for Abbott Laboratories.

James T. McCarthy, MD, is Staff Consultant, Division of Nephrology and Internal Medicine, for the Mayo Clinic and Mayo Foundation, Rochester, MN. He is affiliated with Mayo Health System clinics and hospitals in Minnesota, Wisconsin, and Iowa, and Mayo Foundation Mayo Clinics in Scottsdale, AZ and Jacksonville FL. Dr. McCarthy is the Medical Director of the Mayo-Austin Hemodialysis Unit, and Physician Liaison at Immanuel St. Joseph’s Hospital, Mankato, MN. He is also the Chair of the Mayo Health System (MHS) 1999 Core Goal Work Group, a member of the MHS Regional Operations Committee, a member of the Board of Directors at Immanuel-St. Joseph Hospital, and a member of the Clinical Practice Innovation Review Committee, a Subcommittee of the Mayo-Rochester CPC. Dr. McCarthy belongs to the American Society of Nephrology, the International Society of Nephrology, the Renal Physicians Associations, and the NKF. He has been principal investigator on a number of research studies and has been published over 150 times in different journals and publications. Dr. McCarthy is also a member of the Scientific Advisory Boards of MinnTech Corporation and NxStage, and has received research grants from Schein Pharmaceuticals, GelTex Pharmaceuticals, Bayer Corporation, Amgen, and Luitpoldt Pharmaceutical.

Sharon M. Moe, MD, is Associate Professor of Medicine at Indiana University School of Medicine and Director of Nephrology and Assistant Dean for Research Support at Wishard Memorial Hospital. She is also affiliated with the Richard L. Roudebush Veterans Association Medical Center. Dr. Moe is on the Board of Directors of the NKF of Indiana and a member of the American Society of Nephrology. Dr. Moe is currently a member of the editorial board for the American Journal of Kidney Diseases. Her areas of research and special interests are bone and mineral metabolism including ß2-microglobulin amyloidosis, immunomodulatory effects of vitamin D, and mechanisms of vascular calcification. She has received the NIH K24 award for musculoskeletal diseases in dialysis patients and the VA merit award on ß-2-microglobular amyloidosis. Dr. Moe has been a consultant for Genzyme Corporation, Amgen, Inc., and Bone Care International, and has received grants from Genzyme, Amgen, and Abbott Laboratories.

Isidro B. Salusky, MD, FAAP, is Professor of Pediatrics at UCLA School of Medicine, Program Director of the UCLA General Clinic Research Center, and Director of the Pediatric Dialysis Program. He has a long-standing interest in the fields of growth and nutrition in children with renal failure that has ranged from experimental models to patients treated with maintenance dialysis. Dr. Salusky has done extensive work to characterize the syndromes of renal osteodystrophy in children with chronic renal failure undergoing regular dialysis and postrenal transplantation. He has had more than 150 papers published and is active in many professional societies. During the course of his research, Dr. Salusky has obtained funding from the NIH as well as other nonprofit and commercial organizations. He is a consultant for Genzyme Corporation, Bone Care International, and Abbott Laboratories.

Donald J. Sherrard, MD, is Professor of Medicine and the Chief of Veteran Affairs (VA) Nephrology at the University of Washington Medical School. Dr. Sherrard also completed a fellowship in nephrology at the University of Washington. His areas of research and special interest include calcium and bone as well as chronic renal failure, and he has received a Training Grant from the NIH. Dr. Sherrard has received funding from and consulted with Amgen, Inc., Abbott Laboratories, and Geltex Pharmaceuticals.

Miroslaw Smogorzewski, MD, is Associate Professor of Medicine at the University of Southern California School of Medicine. He is affiliated with the USC Ambulatory Health Center, LAC+USC Medical Center, the USC Healthcare Consultation Center, and the USC University Hospital. Dr. Smogorzewski completed a fellowship in Renal Medicine at Hammersmith Hospital in England and a fellowship in Nephrology at the LAC+USC Medical Center. His chief research interests include heart hypertrophy in chronic renal failure, signal transduction, and cystolic calcium in uremia, the role of parathyroid hormone as a uremic toxin, and metabolic derangement in phosphate depletion, and his main clinical interests are in kidney and renal transplantation and nephrology. In addition to being published many times, Dr. Smogorzewski has also collaborated on the editing of nephrology textbooks He is a member of the American Society of Nephrology, the International Society of Nephrology, and the European Dialysis and Transplant Association.